Sep 23, 2024  
2021-2022 Graduate Bulletin 
    
2021-2022 Graduate Bulletin [ARCHIVED CATALOG]

Course Descriptions


The number system reflects the level of course material and associated rigor. With the exception of upper graduate level and professional courses, any prerequisite restrictions limiting the level of a student accepted into a course shall be specified in a course prerequisites. Courses shall be numbered as follows:

400G-499G Senior and first year graduate level course; graduate credit for non-majors only;
500-599 First year graduate level course; undergraduate and graduate credit;
600-799 Upper graduate level course; open only to graduate students;
800-999 Professional Programs course; open only to students in professional colleges and to students in other colleges offering professional degrees as defined by the Council on Postsecondary Education.

Courses may be approved for variable credits, e.g., (1-3), (2-6), etc. In no case, however, may the total credits exceed the maximum number authorized for the course.

Repeated registration in a course may be allowed if the course description carries the statement: “May be repeated to maximum of … credits.” However, a student may enroll only one time in a specific course during a given semester. Courses with the same number are not considered to be the same course if different identifying titles are an integral part of the record.

Unless indicated in the course description, the number of credits for a course indicates the number of lecture or discussion or class hours.

Below is a list of all graduate level courses (400G and above).

 
  
  • BIO 798 - RESEARCH IN MICROBIOLOGY


    College of Arts & Sciences

    Credits: 1 - 9 (Variable)

    Prerequisite(s):
    Prereq: Consent of instructor.
    Repeatable up to 24 credit hours.
    Crosslisted with: MI 798 
  
  • BME 501 - FOUNDATIONS OF BIOMEDICAL ENGINEERING


    College of Engineering

    Credits: 3

    This course demonstrates the application of diverse engineering principles to analysis and understanding of the structure, function, and control of biological systems. Quantitative measurements and analysis of homeostatic, regulatory, transport, biochemical, and biomechanical processes of the human body.

    Prerequisite(s):
    Prereq: Engineering standing or consent of instructor.
  
  • BME 532 - MODELING OF PHYSIOLOGICAL SYSTEMS


    College of Engineering

    Credits: 3

    This introductory course in mathematical modeling will teach students how to construct simple and elegant models of biological and physiological processes – for instance the absorption and elimination of drugs in the human body or the kinetics of tumour growth in tissue – and to analyze or predict the dynamics of these events by solving the models.

    Prerequisite(s):
    Prereq: MA 214, Engineering standing or consent of instructor; familiarity with computer programming.
  
  • BME 540 - BIOMEDICAL INSTRUMENTATION


    College of Engineering

    Credits: 3

    A comprehensive introduction to major aspects of biomedical instrumentation. Topics include basic concept of medical instrumentation, biopotentials, physiological pressure/flow/respiratory measurement, optical sensing, and clinical applications of all the above. The fundamental mathematics underlying each instrument will be reviewed and an engineering picture of the hardware and software needed to implement each system will be examined.

    Prerequisite(s):
    Prereq: Engineering standing or Consent of Instructor.
  
  • BME 541 - OCCUPATIONAL BIOMECHANICS


    College of Engineering

    Credits: 3

    This course will provide an understanding of physical interaction between workers and their tools, machines, and materials so as to enhance the workers performance while minimizing the risk of musculoskeletal disorders. Discussion of ergonomic methods for measurement, assessment, and evaluation, with major topics including manual materials handling, cumulative trauma disorders, environmental stresses, safety, and legal issues.

    Prerequisite(s):
    Prereq: Engineering standing or with instructor permission.
    Approved for Distance Learning.
    Crosslisted with: MFS 541 
  
  • BME 550 - INTRODUCTION TO BIOMEDICAL IMAGING


    College of Engineering

    Credits: 3

    A comprehensive introduction to bio-medical imaging systems used today, including xray imaging and computed tomography (CT), magnetic resonance imaging (MRI), ultrasound imaging (UI), and diffuse optical tomography (DOT). The course will review the fundamental mathematics underlying each imaging modality, the hardware needed to implement each system, and the image reconstruction and analysis. The class may involve homework, projects, and exams.

    Prerequisite(s):
    Prereq: EE 305, Engineering standing, or consent of instructor.
  
  • BME 571 - MECHANICAL MODELING OF HUMAN MOTION


    College of Engineering

    Credits: 3

    An introduction to mechanical modeling of human motion (lectures) along with application of computational software to model and estimates internal tissues responses to physical demands of several different activities/tasks (lab activities).

    Prerequisite(s):
    Prereq: EM 221, EM 313, Engineering standing; or consent of instructor.
  
  • BME 573 - CELL MECHANICS AND MECHANOBIOLOGY


    College of Engineering

    Credits: 3

    This course will serve as an introduction to cell and tissue level mechanobiology with focus on human physiological and disease processes. The primary focus is to introduce principles of cell-level mechanics in the context of the biology of living organisms, what we term mechanobiology. In effect, we treat biological processes and regulation as another variable(s) that must be accounted for when modeling the mechanical/physical behavior of human tissues. A large amount of the basic principles in this field of study arose as a result of the intense research in the cardiovascular field. We will draw many examples of mechanobiological principles as it relates to the circulatory system. Despite our cardiovascular focus, the basic principles can be applied to the whole range of mechanobiological research conducted in other applications (orthopedics, urological, pulmonary, etc.).

    Prerequisite(s):
    Prereq: EM302 and/or CME/ME 330 (or equivalent fluid mechanics course), Engineering standing; or consent of instructor.
  
  • BME 579 - NEURAL ENGINEERING: MERGING ENGINEERING WITH NEUROSCIENCE


    College of Engineering

    Credits: 3

    A multidisciplinary approach combining engineering principles for systems analysis and control, knowledge of biological control mechanisms, and computational properties of biological neural networks in the development of engineering neural networks for control applications. Topics include: equivalent circuit models for biological neurons and networks, non-linear differential equation representations, biological control strategies for rhythmic movements, design and development of controller for robot function, proposal development and presentation.

    Prerequisite(s):
    Prereq: Engineering Standing or consent of instructor.
    Crosslisted with: EE 579 
  
  • BME 599 - TOPICS IN BIOMEDICAL ENGINEERING; SUBTITLE REQUIRED


    College of Engineering

    Credits: 3

    An interdisciplinary course devoted to detailed study of a topic or current significance in biomedical engineering, such as cellular mechanotransduction, systems biology, and tissue engineering.

    Prerequisite(s):
    Prereq: Engineering standing or Consent of instructor.
    Repeatable up to 6 credit hours.
  
  • BME 602 - PRACTICES OF BIOMEDICAL ENGINEERING


    College of Engineering

    Credits: 3

    Survey of the regulatory, legal, managerial, financial and medical environment in which the biomedical engineering profession is practiced. This course attempts to provide the interface between the theoretical course material taught in the BME curriculum and the realities of the diverse multidisciplinary world that is unique to the biomedical engineer. Outside guest speakers, in class lectures, and case history analyses will be used. Group term project is mandatory.

    Prerequisite(s):
    Prereq: Engineering baccalaureates receive preference.
  
  • BME 609 - BIOMEDICAL ENGINEERING ETHICS


    College of Engineering

    Credits: 1

    This course presents an engineering-based approach to study the system of ethics applicable to biomedical engineering. This course will describe and examine the responsibilities of biomedical engineers to stakeholders, e.g. patients, research subjects, and engineering clients as well as to the legal system (where applicable) and the profession as an entity. As a scholarly discipline, biomedical engineering ethics draws upon principles from subjects such as: the philosophy of science, the philosophy of engineering, and the ethics of technology. Materials from these principles will be used in this course with adaption to the special circumstances attending the practice of Biomedical Engineering.

  
  • BME 622 - NAVIGATIONAL GUIDES FOR BIOMEDICAL PRODUCT DEVELOPMENT


    College of Engineering

    Credits: 3

    This course teaches engineers how biomedical product designs are influenced by government regulations, economic issues, and ethical concerns.

  
  • BME 625 - ANALYSIS OF NONLINEAR BIOMEDICAL SYSTEMS


    College of Engineering

    Credits: 3

    Basic concepts of nonlinear systems: interated maps, dynamical flows, bifurcations, chaos. Modelling and analysis of nonlinear systems: Wiener kernels, white-noise identification, polyspectra, nonlinear time-series models. Extensive discussion of selected biomedical applications.

    Prerequisite(s):
    Prereq: BME 610, BME 615 or EE 640  recommended.
  
  • BME 635 - MAGNETIC RESONANCE INSTRUMENTATION AND MEASUREMENT


    College of Engineering

    Credits: 3

    Laboratory course on the fundamentals of magnetic resonance, instrumentation, measurement, and its biomedical applications. Begins with the nuclear induction experiment and ends with design and implementation of experiments to address engineering and physics problems that relate to the medical field. Instrumentation hardware and software will be taught. Strong engineering/physics and mathematics background is necessary.

    Prerequisite(s):
    Prereq: BME 630 or permission of instructor.
  
  • BME 641 - BIOMEDICAL SIGNAL PROCESSING I


    College of Engineering

    Credits: 3

    Continuous and discrete signals, sampling, Fourier Transform, LaPlace Transform, Z-Transform, correlation and spectral analysis, digital filters.

    Prerequisite(s):
    Prereq: Concurrent enrollment or completion of PGY 412G  or PGY 502 .
  
  • BME 642 - BIOMEDICAL CONTROL SYSTEMS I


    College of Engineering

    Credits: 3

    Homeostatic mechanisms, input-output analysis, steady state and transient response, feedback concepts, system identification and simulation from actual operating data.

    Prerequisite(s):
    Prereq: PGY 502  and ME 440 or equivalent.
  
  • BME 643 - BIOMEDICAL SIGNAL PROCESSING II


    College of Engineering

    Credits: 3

    Stochastic processes, Fourier-based spectral analysis and linear system identification, modern spectral estimation (AR, MA, ARMA), parametric transfer function estimation, time-frequency analysis of nonstationary signals.

    Prerequisite(s):
    Prereq: BME 641 , BME 642 , EE 640  recommended.
  
  • BME 644 - BIOMEDICAL CONTROL SYSTEMS II


    College of Engineering

    Credits: 3

    Biomedical Systems Models, dynamic programming, variational approach to optimal control problems, real-time parameter estimation, adaptive control methods and biomedical applications.

    Prerequisite(s):
    Prereq: BME 641 , BME 642 .
  
  • BME 655 - BIOMEDICAL OPTICAL SPECTROSCOPY AND MICROSCOPY


    College of Engineering

    Credits: 3

    In this course, students will learn about several optical techniques that can be applied to the study of disease and specifically, cancer as well as how research methods can be applied in this context. Laboratory exercises are included to give hands-on experience with technology- specific laboratory skills. Throughout the course, students will complete critiques of the research methods, results and conclusions of peer-reviewed journal articles relating to the application of optical methods. Using the information, they have learned in class, students will complete a short-term research project from a pre-approved list. Ideally, students will use this process to formulate a hypothesis, design an experiment to test their hypothesis, and interpret their findings in terms of whether it tested the hypothesis. Each group of students will be expected to write an Optics Letters style write up on their project’s result.

    Prerequisite(s):
    Prereq: Engineering standing or consent of the instructor.
  
  • BME 662 - TISSUE-IMPLANT INTERFACE


    College of Engineering

    Credits: 3

    Study of the interface between implants and host tissues from both the materials and biological perspective. Structure of the tissue-implant interface; surface characterization of biomaterials; protein adsorption; mechanisms of cell responses; and methods for controlling the tissue-implant interface, with emphasis on orthopedic and cardiovascular applications.

    Prerequisite(s):
    Prereq: BME 688  or consent of instructor.
  
  • BME 664 - NANOBIOENGINEERING AND NANOMEDICINE


    College of Engineering

    Credits: 3

    This is an elective course for graduate students who are interested in learning nano-scale engineering and its applications in biology and medicine. The course covers a broad range of topics in nanobioengineering and nanomedicine, including synthesis, characterization, and functionalization of most common nanomaterials and nanostructures, the interactions between nanoparticles and the biological systems, current state of art in nanomaterial-based molecular imaging, drug/gene delivery, and gene editing and regulation. The topics to be discussed are of considerable importance across different research areas in bioengineering and medicine. Examples will be given to illustrate the applications of nanomaterials. The course will help develop critical reading, scientific writing, and oral presentation skills. Problem-based learning (PBL) will be incorporated throughout the course.

    Prerequisite(s):
    Prereq: Completion of an undergraduate major in bioengineering, biophysics, chemistry & biochemistry, or biological sciences, or permission from the course instructor.
  
  • BME 665 - ADVANCED TISSUE ENGINEERING


    College of Engineering

    Credits: 3

    Tissue engineering can be defined as the application of principles of engineering, biology, materials science, and medicine to restore, maintain, or improve tissue function. This field evolved from the field of biomaterials development, and the term ‘tissue engineering’ has become largely interchangeable with ‘regenerative medicine,’ which also incorporates the research on self-healing. In this course, fundamental engineering and biological principles underlying the field of tissue engineering will be studied, along with case-studies on fabricating specific functional tissues and organs. An open-ended design project is also included in this course. The class will also use examples from the current literature and will rely on interactive in-class and group discussions.

    Prerequisite(s):
    Prereq: Introduction to Biomaterials (BME 488), Human Physiology (PGY 412G  or PGY 502), or consent of the instructor.
  
  • BME 670 - BIOSOLID MECHANICS


    College of Engineering

    Credits: 3

    Application of laws of mechanics to study the behavior of human organ systems. Stress-strain analysis of soft and hard body tissues with emphasis on pulmonary and musculoskeletal systems. Viscoelastic properties.

    Prerequisite(s):
    Prereq: Undergraduate engineering degree or consent of instructor.
  
  • BME 672 - MUSCULOSKELETAL BIOMECHANICS


    College of Engineering

    Credits: 3

    Application of laws of mechanics to study behavior of human musculoskeletal system. Materials science of bone, muscle, tendon are integrated into static and dynamic analyses of isolated (e.g., foot, arm, and hand) and whole body segment.

    Prerequisite(s):
    Prereq: PGY 502 , ME 330 or consent of instructor.
  
  • BME 673 - BIOFLUID MECHANICS


    College of Engineering

    Credits: 3

    Review of the rheology of circulatory processes in the body. Special emphasis on cardiovascular dynamics: pulsatile pressure and flow, vascular impedance, wave propagation/reflection, cardiac dynamics. Special topics. Lecture, three hours with periodic lab demonstrations.

    Prerequisite(s):
    Prereq: Undergraduate engineering degree or consent of instructor.
  
  • BME 688 - BIOMATERIALS SCIENCE AND ENGINEERING


    College of Engineering

    Credits: 3

    Study of biological and man-made materials that perform, improve, or restore natural functions. Structure and properties of connective tissue and commonly implanted metals, ceramics, and polymers; biocompatibility of materials used in orthopedic, soft tissue, and cardiovascular applications.

    Prerequisite(s):
    Prereq: Undergraduate engineering degree or consent of instructor.
  
  • BME 690 - RESEARCH IN BIOMEDICAL ENGINEERING (SUBTITLE REQUIRED)


    College of Engineering

    Credits: 1 - 3 (Variable)

    Individual study related to a special research project. Intended for M.S. candidates who want a research project experience independent of their M.S. thesis work. This course cannot be used to satisfy residency credit requirements. May be repeated to a maximum of six credits. Lecture, one to three hours; laboratory, three to six hours per week.

    Prerequisite(s):
    Prereq: Consent of instructor and graduate standing in BME.
    Repeatable up to 6 credit hours.
  
  • BME 699 - SPECIAL TOPICS IN BIOMEDICAL ENGINEERING (SUBTITLE REQUIRED)


    College of Engineering

    Credits: 1 - 3 (Variable)

    Special topics in biomedical engineering, addressed primarily in a lecture/discussion format. Presentation of focussed or specialized topics that are not available in standard courses. Lecture, three hours; laboratory, 0-2 hours per week. May be repeated to a maximum of nine credits.

    Prerequisite(s):
    Prereq: Consent of instructor and graduate standing in BME.
    Repeatable up to 9 credit hours.
  
  • BME 706 - MANAGEMENT OF TECHNOLOGY


    College of Engineering

    Credits: 3

    Successfulness in developing new technologies relies upon knowing which technology advance, the ultimate scientific limits of that technology, and the forecasted rate of technological change. This course presents curricula that explore the direction of technological change and how this affects the rate and extent of innovation.

  
  • BME 748 - MASTER’S THESIS RESEARCH


    College of Engineering

    Credits: 0

    Half-time to full-time work on thesis. May be repeated to a maximum of six semesters.

    Prerequisite(s):
    Prereq: All course work toward the degree must be completed. Note: Registration for this course is not available via telephone (UK-VIP) or webUK. For enrollment information contact the Graduate School at 257-4905.
  
  • BME 749 - DISSERTATION RESEARCH


    College of Engineering

    Credits: 0

    May be repeated to a maximum of six semesters.

    Prerequisite(s):
    Prereq: Registration for two full-time semesters of 769 residence credit following the successful completion of the qualifying exams. Note: Registration for this course is not available via telephone (UK-VIP) or webUK. For enrollment information contact the Graduate School at 257-4905.
  
  • BME 767 - DISSERTATION RESIDENCY CREDIT


    College of Engineering

    Credits: 2

    Residency credit for dissertation research after the qualifying examination. Students may register for this course in the semester of the qualifying examination. A minimum of two semesters are required as well as continuous enrollment (Fall and Spring) until the dissertation is completed and defended.

    Repeatable up to 99 credit hours.
  
  • BME 768 - RESIDENCE CREDIT FOR THE MASTER’S DEGREE


    College of Engineering

    Credits: 1 - 6 (Variable)

    May be repeated to a maximum of 12 hours.

    Repeatable up to 12 credit hours.
  
  • BME 769 - RESIDENCE CREDIT FOR THE DOCTOR’S DEGREE


    College of Engineering

    Credits: 0 - 12 (Variable)

    May be repeated indefinitely.

  
  • BME 772 - SEMINAR


    College of Engineering

    Credits: 0

    Review of current literature in the field of biomedical engineering, general discussion and presentation of papers on research in biomedical engineering. Lecture, one hour per week. Required for all graduate students in biomedical engineering.

  
  • BME 774 - GRADUATE BME SEMINAR


    College of Engineering

    Credits: 0 - 1 (Variable)

    Scientists and engineers present current research in biomedical engineering. Students are required to prepare for and deliver a seminar on their own research. May be repeated to a maximum of 4 credits.

    Prerequisite(s):
    Prereq: Graduate standing in Biomedical Engineering or consent of instructor.
    Repeatable up to 4 credit hours.
  
  • BME 781 - SPECIAL PROBLEMS IN BIOMEDICAL ENGINEERING (SUBTITLE REQUIRED)


    College of Engineering

    Credits: 1 - 3 (Variable)

    Discussion of advanced and current topics in biomedical engineering. Individual work on research problems of current interest. May be repeated to a maximum of nine credits. Lecture/laboratory hours variable.

    Prerequisite(s):
    Prereq: Approval of instructor.
    Repeatable up to 9 credit hours.
  
  • BME 790 - RESEARCH IN BIOMEDICAL ENGINEERING


    College of Engineering

    Credits: 1 - 9 (Variable)

    Graduate research in any area of biomedical engineering, subject to approval of the Director of Graduate Studies. May be repeated to a maximum of 9 hours.

    Prerequisite(s):
    Prereq: Consent of the Director of Graduate Studies
    Repeatable up to 9 credit hours.
  
  • BME 791 - ADVANCED STUDY PROJECT


    College of Engineering

    Credits: 3

    This is an independent study project, topic to be selected in consultation with the instructor. Purpose is to integrate all materials learned in the program and apply these principles to the solution of an actual problem in biomedical engineering technology. Prerequisites: Permission of instructor and completion of year 1 PBME studies.

  
  • BMI 520 - DESIGNING FOR DATA VISUALIZATION


    College of Medicine

    Credits: 3

    Students will learn techniques for creating effective visualizations of quantitative data using principles from graphic design, perceptual psychology, cognitive science, and user-centered design. Topics include task abstraction, visual encodings of data, use of color, interaction techniques, and methods of evaluation. Data types discussed in the course will include tabular, network, and geospatial data.

    Prerequisite(s):
    Prereq: One programming course, such as CS 115 or equivalent, or permission of instructor.
    Crosslisted with: ICT 520 
  
  • BMI 633 - INTRODUCTION TO BIOINFORMATICS


    College of Medicine

    Credits: 3

    This is an introductory course aimed at a multi-disciplinary audience with an interest in applying the principles of information sciences for obtaining insight into biological processes and systems that can eventually be used to make informed decisions.

    Approved for Distance Learning.
  
  • BMI 730 - PRINCIPLES OF CLINICAL INFORMATICS


    College of Medicine

    Credits: 3

    This course offers an overview of Clinical informatics, which is the application of informatics principles, methods, and tools to support healthcare practice and research activities as well as business processes.

    Approved for Distance Learning.
  
  • BMI 731 - BIOMEDICAL INFORMATION RETRIEVAL


    College of Medicine

    Credits: 3

    This class is an introductory information retrieval class that is focused on biomedical information search engines. Basic IR concepts such index construction, optimization, visualization, and evaluation will be covered. In addition to core IR contexts, students will have an opportunity to learn about search engines, web crawling, and some Web 2.0 technologies based on hands-on exercises and assignments with a focus on techniques that can be used to access, retrieve, organize, and present information. Students will employ an open source indexing engine (e.g., Lemur or Lucene or something similar) to understand how back-end of retrieval engine is effectively and efficiently structured.

    Approved for Distance Learning.
  
  • BMI 732 - BIOMEDICAL ONTOLOGIES AND SEMANTIC WEB TECHNIQUES


    College of Medicine

    Credits: 3

    This course is a conceptual introduction to biomedical ontologies and ontological modeling in biomedicine through Semantic Web techniques. Students will learn about RDF, OWL, description logics, and SPARQL and their role in designing ontologies. Biomedical terminologies such as GO, ICD-9/10, SNOMED-CT, and MeSH will be discussed as case studies.

    Prerequisite(s):
    Prereq: MA 123 (or equivalent) or consent of the instructor.
    Approved for Distance Learning.
  
  • BMI 733 - BIOMEDICAL NATURAL LANGUAGE PROCESSING


    College of Medicine

    Credits: 3

    This course is a technical introduction to the area of biomedical natural language processing (NLP). In the field of biomedical informatics, this focuses on the common steps in extracting information from textual data that arises from biomedical literature and clinical documents. Topics involve n-gram models, tokenization, POS tagging, and parsing.

    Prerequisite(s):
    Prereq: MA 123 (or equivalent) or consent of instructor.
    Approved for Distance Learning.
  
  • BMI 734 - INTRODUCTION TO BIOMEDICAL IMAGE ANALYSIS


    College of Medicine

    Credits: 3

    This class aims to give students a broad overview of biomedical image analysis and imaging informatics. We will introduce the state-of-the-art knowledge to understand, develop, and apply existing methods and software to handle biomedical image data to extract quantitative matrices.

    Approved for Distance Learning.
  
  • BMI 735 - INTRODUCTION TO BIOIMAGE INFORMATICS


    College of Medicine

    Credits: 3

    This class provides an introduction to searching and retrieval in biomedical image analysis and imaging informatics. We will introduce some advanced biomedical image analysis, searching, and retrieval algorithm for fast and efficient image searching and retrieval.

    Prerequisite(s):
    Prereq: BMI 734 : Introduction to Biomedical Image Analysis.
    Approved for Distance Learning.
  
  • BS1 870 - BEHAVIORAL SCIENCE/ NEW ZEALAND


    College of Medicine

    Credits: 4

  
  • BSC 529 - SURVEY OF MEDICAL ANTHROPOLOGY


    College of Medicine

    Credits: 3

    Cross-cultural survey of health, disease, and healing in folk, primitive, and modern pluralistic societies. Biocultural and ethnomedical approaches in medical anthropology.

    Prerequisite(s):
    Prereq: Nine hours of anthropology or consent of instructor.
  
  • BSC 534 - ETHICS AND RESPONSIBILITY IN CLINICAL RESEARCH


    College of Medicine

    Credits: 3

    Clinical scientists need a sound understanding of the ethical principles guiding the conduct of research projects. This course will address issues relevant to ethically sound study design, responsible conduct of research and scientific misconduct. Students will also complete human subjects protection training and learn to conduct research in an ethical manner. During this course, students will engage in both in-class lecture and discussion sessions as well as out of class learning activities (outlined below). The final project for graduate students for this course will serve as a practical application of what is learned during the course to students’ stated research interest. The goal of this course is to provide an overview of ethical considerations when conducting and reporting clinical research, as well as to provide experience in the practice and application of ethics to clinical science. It is assumed by the course directors that students in this course are either actively engaged in clinical research or intend to be involved in clinical research in the near future. This course has been designed around the principle that practical knowledge about how to conduct ethical research should be the focus. A second key principle of this course is that it is student-centered, meaning that it emphasizes the involvement of students in applying the concepts of ethics to their own research interests. The course activities are intended to promote the ethical application of research concepts to students’ areas of interest and to foster practical knowledge that supports students’ own research agendas. The diverse interests and experiences of students and faculty offer opportunities to learn from each other.

    Prerequisite(s):
    Prereq: This course is designed for scholars pursuing research training in clinical and translational science to integrate and apply knowledge obtained in previous training. Permission is required from the Course Director for entry into the class.
  
  • BSC 620 - ORIENTATION TO MEDICAL BEHAVIORAL SCIENCE


    College of Medicine

    Credits: 1

    This course offers a structural exposure of students to the varieties of basic and clinical science research and current issues in healthcare policy under discussion at the University Medical Center. Following weekly attendance at research seminars and clinical rounds, students will present their observations in follow-up discussion groups. May be repeated to a maximum of three credits.

    Repeatable up to 3 credit hours.
    Crosslisted with: CPH 841 
  
  • BSC 625 - FUNDAMENTALS OF BIOSTATISTICS FOR CLINICAL AND TRANSLATIONAL SCIENCE


    College of Medicine

    Credits: 3

    This course is designed to support clinical and translational science students in acquiring an applied understanding of the biostatistical tools and techniques commonly used in the conduct of clinical and translational science research. Through a combination of lectures, readings, demonstrations, discussions, and self-study modules, students will understand and appreciate measurement and statistical challenges that are common to clinical and translational science. Study design, selection of independent and dependent variables, and the selection and use of statistical techniques will be the focus of the course. The course activities are intended to promote the application of biostatistics to research concepts in the students’ areas of interest and to foster practical knowledge that supports students’ own research agendas. If the course is listed as section 001, the format of the course is a standard lecture/discussion. If the course is listed as section 002 the format of the course is a hybrid, with approximately 50% in the classroom and 50% in an on-line format.

    Prerequisite(s):
    Prereq: This course is designed primarily for graduate students pursuing research training in clinical and translational science and who have been admitted to the Clinical and Translational Science training program. All students need permission of the instructor to enroll in this course.
    Approved for Distance Learning.
  
  • BSC 626 - SURVEY OF HEALTH PSYCHOLOGY


    College of Medicine

    Credits: 3

    A survey of the field of health psychology. It will explore the ways in which social and psycho- logical research contribute to an understanding of health and illness behavior.

    Prerequisite(s):
    Prereq: Graduate or professional standing and consent of instructor.
    Crosslisted with: PSY 626 
  
  • BSC 664 - CULTURAL ISSUES IN MENTAL ILLNESS


    College of Medicine

    Credits: 3

    An in-depth discussion of theory and method of the various approaches to cultural and social factors in the etiology, distribution, and treatment of mental illness. Data from non-Western and Western cultures are examined.

    Prerequisite(s):
    Prereq: Enrollment in graduate program in anthropology, sociology, psychology, educational and counseling psychology, or consent of instructor.
    Crosslisted with: ANT 664 , PSY 664  
  
  • BSC 731 - METHODS AND TECHNOLOGIES IN CLINICAL AND TRANSLATIONAL SCIENCE


    College of Medicine

    Credits: 3

    This overview course is designed to introduce the student to the major methods and technologies of clinical and translational science (CTS) with an emphasis on human subjects research. Students learn these core methodologies through classroom discussions, readings, and written portfolio activities that challenge them to apply methodological concepts to their own areas of research interest. Specifically, the course teaches students how to formulate research questions and write literature reviews; apply CTS research methods, including experimental, survey, and qualitative research methodologies, to diverse areas of research by aligning appropriate methodologies to research questions of interest, and enhance interdisciplinary communication skills. It is assumed that students are engaged in research that is consistent with CTS or will become engaged in such research in the near future.

    Prerequisite(s):
    Prereq: Graduate standing. Permission is required from the Course Director for entry into the class.
  
  • BSC 732 - INTERDISCIPLINARY PROTOCOL DEVELOPMENT


    College of Medicine

    Credits: 3

    This course will introduce students to the processes involved in the development and implementation of interdisciplinary research. Students will be introduced to key aspects of the leadership, communication and teamwork involved in interdisciplinary research. Students will also be introduced to the structure and functioning of the NIH and the NIH grant application and review process. Finally, students will apply their knowledge regarding the research methods and technologies of clinical and translational science to develop an NIH-format research grant application that addresses a research topic in their own area of interest. This course is intended for advanced graduate or professional students pursuing focused research training in one of the degree or certificate programs available in clinical and translational science. It is expected students will have completed the course in Methods and Technologies in Clinical & Translational Science (BSC 731 ) prior to this course.

  
  • BSC 733 - SEMINAR IN CLINICAL AND TRANSLATIONAL SCIENCE


    College of Medicine

    Credits: 1

    This seminar course is designed to orient students to clinical and translational research community and activities at the University of Kentucky and to incorporate a multidisciplinary cooperative approach to clinical and translational research. Students are expected to apply their knowledge of effective scientific communication, responsible conduct of research, and methods and technologies of clinical and translational science to ongoing discussions. The course will consist of 7 evening seminars focusing on different topics of clinical and translational research. Students will be required to present a description of their research interests and activities during on seminar. Homework assignments will require students to summarize the key elements of each seminar as related to clinical and translational research and the relevance of these issues to their own Research interests and career plans. Active participation by all members is expected.

    Repeatable up to 3 credit hours.
  
  • BSC 746 - RESEARCH ETHICS AND DILEMMAS


    College of Medicine

    Credits: 3

    This class will utilize case studies for debate, class participation, and papers to help students gain skills to recognize and resolve research dilemmas. Objectives of this class include: (1) understand basic elements of ethical dilemmas; (2) to understand basic ethical theories and frameworks for solving ethical dilemmas; (3) to examine ethical dilemmas within a behavioral or medical science research context; and, (4) to examine ways of eliminating bias and promoting objectivity in a behavioral or medical science research context.

  
  • BSC 750 - HISTORY OF MEDICINE AMONG AFRICAN AMERICANS: IMPLICATIONS FOR HEALTH DISPARITIES


    College of Medicine

    Credits: 3

    This course on the history of medicine among African Americans seeks to provide an understanding of the roots of the African American health deficit. The course will enable students to: 1. Articulate how the earliest encounters between African Americans and Western medical researchers set the stage for health inequities. 2. Engage in and direct thought-provoking discussions of how racist pseudoscientific ideas remain in contemporary society that contributes to health disparities among African Americans. 3. Critically examine the theory of eugenics and social Darwinism and how they are used to justify experimental exploitation and poor medical treatment of African Americans. 4. Understand and identify how historical and contemporary medical issues have contributed to medical ethics of distrust in the African American community.

  
  • BSC 755 - RACE, RACISM & HEALTH DISPARITIES AMONG BLACKS IN THE U.S.


    College of Medicine

    Credits: 3

    This course on racism and health disparities is designed to support graduate studies in the social sciences, allied health, and medical disciplines. This course will briefly review the biological and social history of race in America; critique emerging views on the genetics of race; discuss how the classification/mechanism of ‘race’ operates to contribute to health disparities; explore theoretical frameworks of racism and related measures; differentiate between the terms ‘health inequities’, ‘health inequalities’ and ‘health disparities’; and, examine the biopsychosocial impact of racism on health. Although it is recognized that the discussion of race, racism and health is relevant to other ‘racially-classified social groups’ the course will draw primarily upon the experience of Blacks in the U.S.

  
  • BSC 760 - AGING, HEALTH AND DECISION MAKING


    College of Medicine

    Credits: 3

    This is a doctoral level seminar that provides an overview of behavioral decisional theories (e.g. rational choice, multiattribute utilities models, naturalistic decision making, ethnographic decision models, Janis and Mann’s conflict theory, information processing theory, heuristic models, process tracing models, etc.) and examines research applications of those theories to the health of older adults. Research focuses on decision made by physicans, older adults, caregivers and policy makers. A variety of applications include such decision domains as preventative screening, retirement and financial planning, other medical treatments, self-care, seeking medical care, institutionalization, end-of-life, etc.

  
  • BSC 763 - WOMEN’S TRAUMA & MENTAL HEALTH


    College of Medicine

    Credits: 3

    This course will examine the research on intimate partner violence, mental health, and substance abuse among women. Clinical and legal interventions will also be discussed. Although knowledge of at least basic statistics would be helpful, it is not required for this class.

  
  • BSC 764 - SEMINAR IN HEALTH INEQUITIES


    College of Medicine

    Credits: 3

    This course is designed to critically examine undeniable inequities in the distribution of morbidity and mortality. Students explore linkages between disease burdens and the social economic, and cultural contexts of our rapidly changing world by integrating local, national and international perspectives from social and biomedical sciences.

    Prerequisite(s):
    Prereq: Graduate studies in the social sciences and permission of the instructor
  
  • BSC 765 - ADVANCED SEMINAR IN MEDICAL ANTHROPOLOGY


    College of Medicine

    Credits: 3

    (1) Advanced history and theory of medical anthropology; (2) research design, field work, analysis of data in medical anthropology.

    Prerequisite(s):
    Prereq: Consent of instructor.
    Crosslisted with: ANT 765 
  
  • BSC 766 - CONCEPTS IN MEDICAL SOCIOLOGY


    College of Medicine

    Credits: 3

    A review of sociological concepts and methods which have been applied to the study of health and medicine; the contributions of medical sociology to general sociological theory and to concepts and research on health-related problems of society.

    Prerequisite(s):
    Prereq: Consent of instructor.
    Crosslisted with: SOC 766 
  
  • BSC 767 - DISSERTATION RESIDENCY CREDIT


    College of Medicine

    Credits: 2

    Residency credit for dissertation research after the qualifying examination. Students may register for this course in the semester of the qualifying examination. A minimum of two semesters are required as well as continuous enrollment (Fall and Spring) until the dissertation is completed and defended.

    Repeatable up to 99 credit hours.
  
  • BSC 770 - PSYCHOSOCIAL ISSUES IN HEALTH AND AGING


    College of Medicine

    Credits: 3

    This course will focus on psychosocial issues related to the physical health and functioning of older adults. Topic areas include: theories of aging; age- appropriate research designs; age-related cognitive personality, social and family changes which influence physical health; health behavior and education of older adults; and selected chronic conditions, e.g. Alzheimer’s disease, arthritis, depression, diabetes and stroke.

  
  • BSC 772 - TOPICAL SEMINAR IN MEDICAL BEHAVIORAL SCIENCE


    College of Medicine

    Credits: 1 - 3 (Variable)

    Advanced study of selected topics of current importance in medical behavioral science. May be repeated to a maximum of six credits.

    Prerequisite(s):
    Prereq: Consent of instructor.
    Repeatable up to 6 credit hours.
  
  • BSC 773 - PSYCHOSOCIAL ONCOLOGY


    College of Medicine

    Credits: 3

    This course will introduce the student to the field of psychosocial oncology. Historical and recent developments in the application of behavioral science knowledge and methodology to the understanding and treatment of cancer and the cancer patient will be examined. The role of psychosocial factors in the etiology, prevention, and treatment of cancer will be explored. Emphasis will be placed upon the interaction of biological, psychosocial, and social factors throughout the course of cancer.

    Prerequisite(s):
    Prereq: Graduate standing.
  
  • BSC 774 - FOOD AND FOOD SECURITY IN A CHANGING WORLD


    College of Medicine

    Credits: 3

    This cross-cultural seminar explores the biocultural interactions among food, human biology, and the social, cultural, political and economic factors that shape food-related behaviors and nutritional status of populations. Topics include the social role of food, food beliefs and ideology, the political economy of malnutrition, development strategies and food security, and methods in nutritional anthropology research. Readings and discussions are research focused and approach issues from a variety of theoretical perspectives.

    Prerequisite(s):
    Prereq: ANT 601  or consent of instructor.
    Crosslisted with: ANT 774 
  
  • BSC 775 - HUMAN RESPONSE TO STRESS


    College of Medicine

    Credits: 3

    Human Response to Stress provides an overview of current models and theories of stress, a review of multi-disciplinary approaches to the study of stress in applied settings, and a reading knowledge of selected research findings in the field of stress.

    Prerequisite(s):
    Prereq: Consent of instructor.
  
  • BSC 776 - SEMINAR IN DEPENDENCY BEHAVIOR


    College of Medicine

    Credits: 3

    The course is designed to explore theories of dependency behavior by examining the concept of dependency as it can be applied to the study of various phenomena including alcohol use and abuse; dependence on other psychoactive substances; institutional dependency; dependency in work settings; and poverty and welfare.

    Prerequisite(s):
    Prereq: Consent of instructor.
    Crosslisted with: PSY 776 , SOC 776 , ANT 776 
  
  • BSC 778 - BEHAVIORAL FACTORS IN SELECTED DISEASES


    College of Medicine

    Credits: 3

    An exploration of behavioral science concepts which bear on various physical illnesses. The perspective of the course is interdisciplinary, using concepts from the various behavioral science disciplines.

    Prerequisite(s):
    Prereq: Consent of instructor.
  
  • BSC 779 - BEHAVIORAL FACTORS IN DEATH AND DYING


    College of Medicine

    Credits: 3

    Behavioral concepts are examined which explain reactions of individuals, collectivities and social institutions to the phenomenon of death.

    Prerequisite(s):
    Prereq: Consent of instructor.
  
  • BSC 781 - HEALTH RELATED BEHAVIORS: MODELS AND APPLICATIONS


    College of Medicine

    Credits: 3

    The focus of the course will be models of health- related behavior, including the Health Belief Model, the Theory of Planned Behavior, Social Cognitive Theory, and Stages of Change Theory, discussing development of the models, similarities and differences, strengths and weaknesses, and suggestions for future model development. We will also look at the extent to which the models explain behavior and behavior change empirically, and how useful they may be (or not be) in the development of primary and secondary prevention interventions.

    Prerequisite(s):
    Prereq: Consent of instructor.
  
  • BSC 782 - WOMEN HEALTH AND AGING


    College of Medicine

    Credits: 3

    This class explores the issues related to health and well-being among older women. Using a multidisciplinary approach that blends humanities, social and medical science and public policy, the course examines social, economic and cultural contexts of chronic physical and mental health.

    Prerequisite(s):
    Prereq: Upper level/graduate class in social science.
    Crosslisted with: GRN 782 
  
  • BSC 787 - BIOBEHAVIORAL PERSPECTIVES ON DRUG AND ALCOHOL ABUSE AND DEPENDENCY


    College of Medicine

    Credits: 3

    This seminar course is designed to survey major tops, concepts and issues pertinent to the field of drug and alcohol abuse and dependence. The course will consist of 14 weekly presentations by instructors followed by open discussion of the presentation and assigned readings by class members. Active participation by all members is expected. Each weekly presentation is designed to provide a general overview of the current state of knowledge (e.g., theory, methods, ethics, and review of classic and/or exemplary studies) in a given area of drug and alcohol abuse and dependence research. Discussions are intended to integrate the information across traditional and disciplinary boundaries.

    Prerequisite(s):
    Prereq: This course is an introductory graduate level course intended for students pursuing focused research training in or more areas of drug and alcohol abuse and dependence. No special prerequisites, other than graduate standing are necessary.
  
  • BSC 788 - DRUG ABUSE: CONTEMPORARY THEORIES & ISSUES


    College of Medicine

    Credits: 3

    This course is designed to familiarize students with major concepts and current issues in the field of substance abuse research.

  
  • BSC 790 - RESEARCH IN MEDICAL BEHAVIORAL SCIENCE


    College of Medicine

    Credits: 1 - 6 (Variable)

    Individually directed research and reading in particular aspects of medical behavioral science under the supervision of one or more members of the faculty. May be repeated up to a maximum of 12 hours.

    Prerequisite(s):
    Prereq: Consent of instructor.
    Repeatable up to 12 credit hours.
  
  • BSC 814 - PATIENTS, DENTISTS AND SOCIETY I


    College of Medicine

    Credits: 1

    This course aims to orient the student to the place health and health professions play in modern cultures. Recognition of their own social assumptions and values and those of persons of different backgrounds is encouraged. Understanding, predicting, and changing dental patient behavior from a social standpoint is emphasized.

    Repeatable up to 4 credit hours.
    Crosslisted with: CDE 814 
  
  • BSC 815 - FIRST-YEAR ELECTIVE, BEHAVIORAL SCIENCE


    College of Medicine

    Credits: 1 - 3 (Variable)

    With the advice and approval of his or her faculty adviser, the first- year student may choose approved electives offered by the Department of Behavioral Science. The intent is to provide the student an opportunity for exploration and study in an area which supplements and/or complements required course work in the first-year curriculum. Pass-fail only.

    Prerequisite(s):
    Prereq: Admission to first year, College of Medicine.
  
  • BSC 824 - COMMUNICATION IN THE DENTAL HEALTH CARE SETTING


    College of Medicine

    Credits: 1

    This course aims to improve the student’s ability to communicate with patients and the public in an empathetic and professional manner. Methods of obtaining necessary health information from all types of patients are taught.

    Prerequisite(s):
    Prereq: Second year standing in the College of Dentistry.
    Repeatable up to 4 credit hours.
    Crosslisted with: CDE 824 
  
  • BSC 825 - SECOND-YEAR ELECTIVE, BEHAVIORAL SCIENCE


    College of Medicine

    Credits: 1 - 4 (Variable)

    With the advice and approval of his or her faculty adviser, the second-year student may choose approved electives offered by the Department of Behavioral Science. The intent is to provide the student an opportunity for exploration and study in an area which supplements and/or complements required course work in the second-year curriculum. PASS-FAIL ONLY.

    Prerequisite(s):
    Prereq: Admission to second year medical curriculum and approval of advisor.
    Repeatable up to 27 credit hours.
  
  • BSC 850 - ELECTIVE IN BEHAVIORAL SCIENCE


    College of Medicine

    Credits: 4

    With the advice and approval of the faculty adviser and the Student Progress and Promotions Committee, the fourth-year student may choose approved electives offered by the various departments in the College of Medicine. The intent is to provide the student an opportunity to develop his fund of knowledge and clinical competence.

    Prerequisite(s):
    Prereq: Admission to the fourth-year College of Medicine and/or by permission of Third and Fourth Year Curriculum and Student Progress Committee.
  
  • BSC 880 - TREATMENT OF DENTAL FEAR


    College of Medicine

    Credits: 1

    This advanced course in the treatment of dental fear is intended to prepare the student to manage very fearful dental patients. Topics covered include etiologies, diagnosis and types, relaxation and distraction, and case histories. Note: Scheduling for the course will take place outside of regularly scheduled clinic/class time.

    Prerequisite(s):
    Prereq:CDS 823   and consent of course director.
    Crosslisted with: CDE 880  
  
  • BST 535 - INTRODUCTION TO R PROGRAMMING


    College of Public Health

    Credits: 3

    BST 535 provides an introduction to R programming with an emphasis on exploration, manipulation, and visualization of data sets. Students will learn application of statistical techniques in R, statistical programming, and practice effective communication of one’s findings.

  
  • BST 600 - INTRODUCTION TO BIOSTATISTICAL METHODS


    College of Public Health

    Credits: 3

    BST 600 covers basic statistical methods that are commonly encountered in health-related research. Major topics include descriptive statistics, estimation and hypothesis testing for means and proportions, correlation, and regression, with a special focus on the computation and interpretation of these methods for analyzing health data.

    Prerequisite(s):
    Prereq: College level algebra or equivalent.
  
  • BST 631 - DESIGN AND ANALYSIS OF HEALTH SURVEYS


    College of Public Health

    Credits: 3

    BST 631 covers design and analysis issues associated with well-known national health surveys, including reliability and validity of measurements, instrument validation, sampling designs, weighting of responses, and multiple imputations. Students will learn how to use statistical software to analyze data from complex survey designs.

    Prerequisite(s):
    Prereq: BST 600 .
    Approved for Distance Learning.
  
  • BST 635 - DATABASES AND SAS PROGRAMMING


    College of Public Health

    Credits: 3

    BST 635 covers basic concepts on databases with applications to public health. Students will learn how to program in SAS, the leading statistical analysis system. SAS skills include managing data, using SQL, generating descriptive statistics, visualizing data, writing reports, writing MACROs, and programming using SAS.

    Approved for Distance Learning.
  
  • BST 636 - ANALYTIC METHODS FOR MINING HEALTHCARE DATA


    College of Public Health

    Credits: 3

    BST 636 covers statistical techniques for issues associated with the exploration of large public health data sets and the development of models from such data sets. The practical issues involved in analyzing large observational healthcare data will be addressed with a focus on appropriate interpretations and the effective communication of results.

    Prerequisite(s):
    Prereq: BST 600  and BST 635  or consent of instructor.
  
  • BST 655 - INTRODUCTION TO STATISTICAL GENETICS


    College of Public Health

    Credits: 3

    BST 655 presents an introduction to the statistical methodologies used today to investigate genetic susceptibility to complex diseases. The course focuses on linkage and association analysis with applications to real-world data. Commonly used (and freely available) software will be presented and used throughout. Because the field is constantly evolving, a focus of the material for this course will be recent statistical human genetics literature.

    Prerequisite(s):
    Prereq: STA 580  or equivalent.
    Crosslisted with: STA 655 
  
  • BST 661 - SURVIVAL ANALYSIS


    College of Public Health

    Credits: 3

    BST 661 provides an introduction to common concepts and methods used in the display and analysis of time to event data. Topics include censoring, hazard rates, estimation of survival curves, regression techniques, applications to human health studies.

    Prerequisite(s):
    Prereq: BST 600 .
  
  • BST 662 - APPLIED LONGITUDINAL DATA ANALYSIS


    College of Public Health

    Credits: 3

    BST 662 presents applied statistical techniques for analyzing data from longitudinal studies and repeated measures experiments that occur frequently in public health, clinical and translational trials, and health outcomes research. This course will cover linear mixed models, generalized linear mixed models and generalized estimating equations as they apply to the analysis of correlated data.

    Prerequisite(s):
    Prereq: BST 600 .
  
  • BST 663 - ANALYSIS OF CATEGORICAL DATA


    College of Public Health

    Credits: 3

    BST 663 is an applied first course in the analysis of categorical data. Topics for categorical data include methods for proportions, rates, ratios, relative risks, risk ratios, and odds ratios. Cochran-Mantel- Haenzel tests, exact tests, logistic regression, time to events and life table methods, and generalized least square methods will be discussed with applications in public health, clinical and translational trials.

    Prerequisite(s):
    Prereq: BST 600 , CPH 603 , or instructor consent.
  
  • BST 664 - DESIGN AND ANALYSIS OF CLINICAL TRIALS


    College of Public Health

    Credits: 3

    BST 664 covers the fundamental concepts used in the design of clinical and translational trials with an introduction to statistical methodology associated with trial data analysis.

    Prerequisite(s):
    Prereq: BST 600  or consent of instructor.
    Approved for Distance Learning.
  
  • BST 675 - SIMULATION BASED INFERENCE FOR HEALTH DATA SCIENCE


    College of Public Health

    Credits: 3

    BST 675 covers the fundamentals of probability and inference through simulation. Topics are focused on methodology used in health data science and include, but are not limited to, random variables, independence, discrete and continuous distributions, confidence intervals, hypothesis testing, and efficient estimators.

    Prerequisite(s):
    Prereq: BST 600  or consent of instructor and two semesters of calculus.
  
  • BST 676 - THEORY FOR BIOSTATISTICS METHODS


    College of Public Health

    Credits: 3

    BST 676 covers the theoretical underpinnings of probability and inference as it relates to methodology in public health. Topics include, but are not limited to, random variables, independence, discrete and continuous distributions, confidence intervals, hypothesis testing, and efficient estimators.

    Prerequisite(s):
    Prereq: BST 675 .
  
  • BST 681 - LINEAR REGRESSION


    College of Public Health

    Credits: 3

    BST 681, the first in a two-semester sequence in regression modeling, covers linear regression models for normally distributed outcomes. The course will cover simple and multiple linear regression, estimation, interpretation, hypothesis testing, model building and diagnostics, matrix algebra for regression, and an introduction to design of experiments. The course will include the use of computing tools to apply these models to real data.

    Prerequisite(s):
    Prereq: BST 600  or consent of instructor.
  
  • BST 682 - GENERALIZED LINEAR MODELS


    College of Public Health

    Credits: 3

    This course, the second in a two-semester sequence in regression modeling, covers regression models for outcomes which are not normally distributed, such as binary and count data. The course will cover the generalized linear model framework, multivariate maximum likelihood theory, logistic regression, Poisson regression, and nominal and ordinal logistic regression models, as well as approaches for building models and checking assumptions. The course will include the use of computing tools to apply these models to real data.

    Prerequisite(s):
    Prereq: BST 675  and BST 681  or consent of instructor.
 

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